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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCSH
All Species:
43.94
Human Site:
S89
Identified Species:
80.56
UniProt:
P14314
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P14314
NP_001001329.1
528
59425
S89
Y
K
P
L
Y
I
P
S
N
R
V
N
D
G
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_542057
593
66107
S144
Y
K
P
L
Y
I
S
S
R
W
V
N
D
G
V
Cat
Felis silvestris
Mouse
Mus musculus
O08795
521
58774
S89
Y
K
P
L
Y
I
L
S
S
R
V
N
D
G
V
Rat
Rattus norvegicus
NP_001100276
525
59200
S88
Y
K
P
L
Y
I
L
S
S
R
V
N
D
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510649
692
76488
S128
Y
K
P
Q
Y
I
P
S
S
R
V
N
D
G
V
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086185
514
57354
S92
Y
K
P
Q
Y
I
P
S
S
R
I
N
D
G
I
Zebra Danio
Brachydanio rerio
NP_957347
529
59566
S94
Y
K
P
T
F
I
P
S
S
R
I
N
D
G
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609844
548
61521
S104
H
Q
P
V
N
I
P
S
S
Q
V
Q
D
G
I
Honey Bee
Apis mellifera
XP_625125
493
56012
S100
H
K
P
R
Y
I
P
S
T
W
V
N
D
G
V
Nematode Worm
Caenorhab. elegans
NP_496073
507
58044
T98
H
K
G
N
F
I
P
T
N
R
V
N
D
K
L
Sea Urchin
Strong. purpuratus
XP_789169
523
60041
S73
Y
R
P
Y
Y
I
P
S
S
R
V
N
D
G
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146004
602
67827
S93
H
T
P
V
T
I
F
S
S
R
V
N
D
G
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04924
702
79889
F102
G
G
K
V
N
K
Y
F
Y
C
D
N
K
G
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
80.9
N.A.
86.7
85.2
N.A.
53.6
N.A.
62.3
62.3
N.A.
38.3
41.4
36.7
43.7
Protein Similarity:
100
N.A.
N.A.
83.9
N.A.
92.9
91.6
N.A.
61.9
N.A.
77
76.7
N.A.
53.2
57.9
56.4
59.4
P-Site Identity:
100
N.A.
N.A.
80
N.A.
86.6
86.6
N.A.
86.6
N.A.
73.3
66.6
N.A.
46.6
73.3
53.3
73.3
P-Site Similarity:
100
N.A.
N.A.
80
N.A.
93.3
93.3
N.A.
93.3
N.A.
93.3
93.3
N.A.
86.6
80
80
93.3
Percent
Protein Identity:
N.A.
31.8
N.A.
N.A.
21.9
N.A.
Protein Similarity:
N.A.
48.6
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
53.3
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
80
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
0
93
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
16
0
8
8
0
0
0
0
0
0
8
% F
% Gly:
8
8
8
0
0
0
0
0
0
0
0
0
0
93
0
% G
% His:
31
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
93
0
0
0
0
16
0
0
0
39
% I
% Lys:
0
70
8
0
0
8
0
0
0
0
0
0
8
8
0
% K
% Leu:
0
0
0
31
0
0
16
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
16
0
0
0
16
0
0
93
0
0
0
% N
% Pro:
0
0
85
0
0
0
62
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
16
0
0
0
0
0
8
0
8
0
0
0
% Q
% Arg:
0
8
0
8
0
0
0
0
8
70
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
85
62
0
0
0
0
0
0
% S
% Thr:
0
8
0
8
8
0
0
8
8
0
0
0
0
0
0
% T
% Val:
0
0
0
24
0
0
0
0
0
0
77
0
0
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% W
% Tyr:
62
0
0
8
62
0
8
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _